2023-04-26 01:31:32
delivery time2023-04-26 10:31
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(Seoul = Yonhap News) Correspondent Han Seong-gan = For hypertensive patients in their 50s and older, a study found that aggressive treatment to lower systolic blood pressure, the highest blood pressure, to 120 mmHg is more effective in preserving brain health than standard treatment that lowers systolic blood pressure to below 140 mmHg. came out
University of Texas Health Sciences Center Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases Professor Mohammad Harves of Radiology Research Team conducted ‘Systolic Blood Pressure Intervention Trial’ (SPRINT) An analysis of the data revealed this fact, the science news site EurekAlert of the American Association for the Advancement of Science (AAAS) reported on the 25th.
SPLINT ran from 2010 to 2016. The follow-up period was 4 years.
A total of 670 participants in the clinical trial were all hypertensive patients.
Of these, 355 (mean age 67.7 years, male 56.3%) received aggressive treatment to lower systolic blood pressure to 120 mmHg, and 315 (mean age 67 years, male 63.2%) received standard treatment to lower systolic blood pressure below 140 mmHg. received
They underwent brain MRI scans before and following the clinical trial and during the follow-up period.
The research team intensively analyzed all the data collected so far over two years from 2020.
The analysis showed that the aggressive treatment group had fewer white matter lesions in the deep frontal and occipital lobes of the brain and improved cerebral blood flow than the standard treatment group.
White matter lesions may also be associated with cognitive impairment, accelerated brain aging, and Alzheimer’s disease, the research team said.
The cerebral cortex is darker than the inner part of the cerebrum, so it is called gray matter, and the inner part is called white matter. Gray matter consists of nerve cell bodies and capillaries, and white matter appears white because of the myelin sheath surrounding axons, which are branches of nerve cells.
The aggressive treatment group also improved blood flow to the occipital lobe, parietal lobe, frontal gyrus, and cuneus.
The research team explained that this result shows that aggressive treatment of hypertension in the elderly can help preserve cognitive function by suppressing cerebrovascular damage.
The American Heart Association (AHA) and the American College of Cardiology (ACC), the two major heart-related societies in the United States, announced a new hypertension guideline in 2017 that drastically lowered the systolic blood pressure from 140 mmHg to 130 mmHg.
The findings were published in the latest issue of JAMA Network Open, the journal of the American Medical Association.
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