2023-04-20 17:28:48
Canadian researchers have developed new cells designed to defeat leukemia resistant to conventional treatments of this disease which is the most frequently diagnosed type of cancer in children.
The cells developed by Dr. Michel Duval and his team from the hematology-oncology department of the CHU Sainte-Justine activate the killer cells (NK cells) of the immune system which will then destroy cancer cells, reports the Canadian press which quotes a recently published scientific study. The cells created were cultured from cord blood, collected and stored following deliveries. They resemble sentinel cells that normally recruit NK cells, but are absent in patients who have undergone bone marrow transplantation to treat their disease.
Unlike sentinel cells, however, these cells only mobilize NK cells, without the risk of activating other immune cells that might attack the patient’s body, it is explained.
Preclinical cell trials have shown this treatment to be effective for several types of leukemia, including lymphoblastic leukemia, myeloid leukemia and neuroblastoma, the study said.
“There is no more effective way of activating NK cells once morest leukemia than ours”, welcomed Michel Duval, indicating that the steps are underway for approval in order to launch a clinical trial of phase 1 from 2024.
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