Protection once morest cardiovascular disease from soybeans?
Consumption of different soybeans appears with a lowering of the Cholesterinspiegels and in particular the unhealthy LDL cholesterol connected, which is considered a risk factor for cardiovascular diseases.
In a new study involving experts from University of Illinois at Urbana-Champaign were the compositions and effects of nineteen soybean varieties examined for hepatic cholesterol metabolism and LDL oxidation. The results are published in the journal “Antioxidants” released.
Different protein hydrolysis of soybeans
The team found that different varieties of soybeans digested under simulated gastrointestinal conditions had different Proteinhydrolyse exhibited. Protein hydrolysis is the process of breaking down proteins into smaller ones peptides and amino acids by enzymes called proteases.
The researchers were able to classify the studied varieties of soybeans according to their composition (high/low glycinine:β-conglycinin ratio) and their ability to inhibit HMGCR in different classes classify
Five Soybean Varieties Beneficial for Cholesterol
Finally became five types of soy determines which is beneficial to the cholesterol levels and the LDL cholesterol affect. These beans produced different profiles of peptides.
The results are consistent with a previous study published in the “Journal of Nutrition“ was published and had investigated whether one Lower cholesterol with soy protein can.
HMGCR in soybeans reduces cholesterol levels
In the new study, the experts also found that the five types of soybeans effectively reduce cholesterol levels by Enzym HMGCR in fatty acid-stimulated HepG2 hepatocytes in different ways.
HMGCR plays a crucial role in Cholesterinstoffwechsel and is also the goal for one Treatment with statinswhich aims to reduce the level of cholesterol in the blood to reduce.
Furthermore, the LDL-Oxidation disabled and the Triglyceridproduktion and the so-called inhibited cholesterol esterification.
Which soybeans are good for lowering cholesterol?
According to the team, it showed that soybean varieties, which a low glycinin:β-conglycinin ratio showed a better potential to regulate the Cholesterol and LDL homeostasis had.
The researchers conclude from the results of the new study that a nutrition with Soy flour with a higher proportion β-Conglycinin helps maintain healthy cholesterol homeostasis in the Leber maintain and at the same time the cardiovascular function improved. (as)
Author and source information
This text corresponds to the requirements of medical specialist literature, medical guidelines and current studies and has been checked by medical professionals.
Sources:
- Miguel Rebollo-Hernanz, Neal A. Bringe, Elvira Gonzalez de Mejia: Selected Soybean Varieties Regulate Hepatic LDL-Cholesterol Homeostasis Depending on Their Glycinin:β-Conglycinin Ratio; in: Antioxidants (veröffentlicht 22.12.2022), Antioxidants
- Sonia Blanco Mejia, Mark Messina, Siying S Li, Effie Viguiliouk, Laura Chiavaroli, et al.: A Meta-Analysis of 46 Studies Identified by the FDA Demonstrates that Soy Protein Decreases Circulating LDL and Total Cholesterol Concentrations in Adults; in: Journal of Nutrition (veröffentlicht 22.04.2019), Journal of Nutrition
Important NOTE:
This article contains general advice only and should not be used for self-diagnosis or treatment. He can not substitute a visit at the doctor.
