The IRIS register® Registry (Intelligent Research in Sight) has powered several big data studies this year, most of which will be presented and discussed at Gather AAO 2022, the 126thannual meeting of theAmerican Academy of Ophthalmology.
Launched in 2014, the IRIS Registry is the nation’s first and largest comprehensive eye disease registry. It currently includes data from nearly 75.4 million unique patients and 454 million patient visits.
The IRIS registry continues to provide the real-world medical information we need to improve outcomes for our patients. The data presented at AAO 2022 will help us better understand risk factors, improve data analysis methods, and understand the effectiveness of different technologies. »
Flora Lum, MD, Vice President for Quality and Data Science, American Academy of Ophthalmology.
Research to be presented includes:
Articles et posters
- Emulation of Comparison of AMD Treatment Trials (CATT). This analysis provides further evidence that clinical trial populations do not reflect real-world patient populations. However, the authors claim that advanced methodologies can solve this problem. Session PO362, Durga Borkar, MD. On demand.
- Neuromyelitis optica and multiple sclerosis. This research demonstrates the benefit of combining data from two different medical registries (IRIS registry and Axon registry) to compare visual outcomes of neurological diseases. Session PA009, Heather Moss, MD, PhD. In person and on request.
- Use of intracanalicular dexamethasone inserts in real-world patients. Intracanalicular dexamethasone (DEX) inserts have been used following a surgery cataracts most commonly in patients with ocular surface conditions such as dry eye. Session PO021, Michael Mbagwu, MD. On demand.
- Safety of Dexamethasone intracanalicular inserts. The results show a high rate of positive safety outcomes in cataract surgeries using DEX. Session PO002, Robert Chang, MD. On demand.
- Endophthalmitis rate in cataract surgery. The risk of postoperative endophthalmitis was higher in people with a recent diagnosis of uveitis and in those on immunosuppressive therapy. Session PO330, Hashem Ghoraba, MBCHB. On demand.
- Treatment of acute retinal necrosis (ARN) and retinal detachment (DR). The largest study to date of patients with ARN finds that treatment with intravitreal antivirals and early pars plana vitrectomy did not improve DR rates. Session PA027, Ines Lains, MD. In person and on request.
- Risk of rhegmatogenous retinal detachment (RRD) in the patient’s eye. The analysis shows that the risk of retinal detachment in the left eye is higher in men, people under 60 and active smokers. Session PO337, William Kearney, MS. Sur demande.
- Effectiveness of minimally invasive glaucoma surgery. Although minimally invasive glaucoma surgeries and traditional incisional glaucoma surgeries both reduce IOP significantly, the reduction in medication at one year was greater in patients who underwent traditional surgery. Session PA001, Shan Lin, MD. In person and on request.
- Combined cataract and glaucoma surgery or stand-alone surgery. Researchers evaluated the effectiveness of trabeculectomy and glaucoma drainage device implantation combined with phacoemulsification compared to stand-alone procedures. They found that stand-alone procedures were more likely to require reoperation. Session PO124, Elizabeth Catherine Ciociola, BA. On demand.
- Causes of childhood blindness United States. More than 50% of blind children in the United States had a treatable disease. This was a unique cross-sectional view of childhood blindness, analyzing data from 81,164 children with visual acuity of 20/200 or less in their better eye. Session PA035, Hang Woong Lim, MD, PhD. In person and on request.
Symposium
Scientific discoveries from Big Data from the RPB/AAO Prize for research on the IRIS registry
Four winners discuss their studies.SYM47, Chairman: Maria Woodward, MD, MS. In person and on request.
- Glaucoma Surgery in Children-;Ta Chen Chang, MD
- Acanthamoeba Keratitis Treatment and results-;Jennifer Patnaik, PHD
- Loss to follow-up in patients with glaucoma-;Andrew Williams, MD
- Visual Consequences of Herpes Zoster-;Nakul Shekhawat, MD
To find out more regarding the IRIS register, visit the site:www.aao.org/iris-registry
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