Scientists at the California Institute of Technology developed wearable sensor for continuous monitoring of human biological markers by his sweat. The device extracts data from a very small volume of sweat and does so with unparalleled accuracy across a wide range of metrics. Such sensors will help to monitor the state of health much easier and with greater accuracy, which will be used in many areas of life.
Image Source: Caltech
Previous versions of these sensors relied on enzymes built into them to detect a limited number of biomarker compounds. The problem was that the sensors quickly consumed active substances. The new technology does not include such consumables, but uses a kind of imprint – molecularly imprinted polymers that are designed to capture specific molecules and nothing more.
The sensors proposed by scientists can detect eight essential amino acids and a whole range of vitamins. The controlled molecules from the sweat each penetrate their own imprints (molds) and in this case prevent the flow of electric current from the bottom of the mold to the outside. The more desired molecules in the composition of sweat, the weaker the electrical signal in each channel (the more imprints are filled with molecules). Resetting such a system is very simple – just apply an increased potential to the sensors and the molecules will shake out of the molds or be destroyed. No consumables are required for the sensors – they are ready to go once more.
To analyze the biochemical composition of sweat, a very small volume is required. This is another highlight of the development – the ability to draw in tiny portions of sweat through microchannels. Sweat secretion, by the way, is stimulated electrically (on the sensors, the stimulator electrodes are represented by two large arcs). Since little sweat is needed, the electrical stimulus is very weak and does not cause discomfort.
“This approach allows us to discover a range of new critical nutrients and metabolites. We can track when we eat and see how our nutrient levels change. – the authors of the development explain. “It tracks not only nutrients, but also hormones and medications. This can provide continuous monitoring for many health conditions.”
If you notice an error, select it with the mouse and press CTRL + ENTER.
