san diego, August 5, 2022 /PRNewswire/ — Alzheimer’s Association International Conference®(AAIC)®) The new study reported in 2022 covered a wide range of Alzheimer’s and dementia research, including aging and the basic biology of the brain, risk factors and prevention strategies, care and living with the disease.
The AAIC is the premier annual forum for presentation and discussion of the latest Alzheimer’s and dementia research. This year’s hybrid conference event, held online and face-to-face in San Daygo, attracted more than 9,500 attendees and hosted more than 4,000 scientific presentations.
Vice President of Medical and Scientific Relations, Alzheimer’s Association Heather M. Snyder (Heather M. Snyder) Ph. D.“This is an exciting time for Alzheimer’s and dementia research, with record public and private research investment,” said Dr. “Researchers are advancing our understanding of the disease by exploring biomarkers, discovering ways to reduce risk, and bringing promising therapies and diagnostic tools into clinical testing. We are leading the fight once morest disease through convening, publishing, partnerships, advocacy and service.”
therapeutic Development, clinical trial result
Alzheimer’s Associationhighlighted the results of various clinical trials at AAIC 2022. Encouraging and supporting diverse treatment pipelines is essential to achieving the association’s vision of a world free of Alzheimer’s and all other dementias. Here are two examples.
EXERT Researchis the longest phase 3 exercise study in the elderly with mild cognitive impairment (MCI). The results first reported at AAIC 2022 are particularly noteworthy following clinical trials were conducted during the COVID-19 pandemic. 80% of the participants followed the exercise regimen and completed the study. After 12 months, people with mild cognitive impairment (MCI) showed no cognitive decline in both the aerobic exercise group and the stretching group. A control group of other older adults with mild cognitive impairment (MCI) showed significant cognitive decline for 12 months. The results of the EXERT study suggest that regular physical activity can protect brain cells from damage, even for activities that don’t require much effort, such as stretching.
at AAIC 2022 T3D Therapeutics(Therapeutics)Is T3D-959of 2award examreported positive interim results. This test is a test to find a way to overcome the brain’s insulin resistance and restore the brain’s metabolic health. These encouraging preliminary results are a positive sign, with final results expected in 2023. As our understanding of the biological underpinnings of Alzheimer’s disease expands, so will the opportunities to advance novel approaches such as T3D-959.
Alzheimer’s Association (AAIC) Alzheimer’s Network for Treatment and Diagnosis(ALZ-NET) announced the launch. ALZ-NET will collect long-term clinical and safety data from patients treated with an FDA-approved drug for Alzheimer’s disease in a real clinical setting. ALZ-NET is the first network developed specifically for an FDA-approved Alzheimer’s treatment, and will gather evidence of efficacy and side effects over the long term.
memory decline and Recognition function degradation and Relevant racist experience
Experiences of structured, interpersonal, and institutional racism are associated with low memory scores and cognitive decline in middle age and old age, a trend particularly pronounced among blacks.
- In a study of approximately 1,000 middle-aged adults (55% Latinos, 23% blacks, and 19% whites) living in the community, exposure to interpersonal and institutional racism was associated with lower memory scores and The association was found to be strongest in black individuals. Experiences of structural racism were associated with lower episodic memory in all racial and ethnic groups in the study.
- In a study of 445 Asian, black, Latino, white, and multiracial people over the age of 90, individuals who experienced widespread discrimination during their lifetime had lower long-term memory scores in old age compared to those who experienced little or no discrimination .
dementia dangerous increase and Relevant Pregnant middle hypertensive of disease Record
Hypertensive disease during pregnancy (HDP), a hypertensive condition including chronic/gestational hypertension and preeclampsia, is closely associated with heart disease in later life, but so far few studies have linked these disorders to cognitive abilities. Multiple studies from AAIC 2022 have found that experiencing hypertensive disease (HDP) during pregnancy is associated with an increased risk of vascular dementia and accelerated brain aging.
- Women with a history of HDP are more likely to develop vascular dementia, which impairs thinking function in old age, due to conditions that block or reduce blood flow to the brain, compared to women who did not experience hypertensive disease during pregnancy.
- HDP, particularly the experience of hypertension during pregnancy, was associated with white matter pathology, a predictor of cognitive decline following 15 years of pregnancy.
- Women with a history of severe preeclampsia had significantly higher levels of beta-amyloid, a brain change associated with Alzheimer’s, than women who did not experience hypertensive disease during pregnancy.
corona19as Due to continuous smell loss is long term lasting Recognition function problem and closely related and, intensive care unit(ICU) long time hospitalization is elderly dementia risk two aboard increase number have
A number of studies reported at AAIC 2022 have uncovered new insights into factors that may predict, augment and protect the impact of COVID-19 and the pandemic on memory and thinking skills. An Argentinean research group found that persistent loss of smell might better predict long-term cognitive impairment and dysfunction than the severity of the initial COVID-19 disease. A large study group in nine Latin American countries found that positive life changes experienced during the pandemic (such as spending quality time with friends and family) reduced the negative effects of the pandemic on memory and thinking skills. Rush Alzheimer’s Center in Chicago (Rush Alzheimer’s According to the Disease Center, intensive care unit (IUC) admission was associated with a doubling of the risk of dementia among older adults. This finding might be an important finding given the sharp increase in ICU admissions during the COVID-19 pandemic.
ultra-finished food, Recognition function degradation to accelerate number I have
A study presented at AAIC 2022 found that people who ate a lot of ultra-processed foods had a faster rate of cognitive decline. Researchers studied 10,775 people over an eight-year period and found that eating high amounts of ultra-processed foods (more than 20% of the daily intake) was associated with a 28% faster rate of decline in cognitive function on overall cognitive function scores, including memory, language fluency, and executive function. found that Ultraprocessed foods go through many industrial processes and contain high amounts of fats, sugars, salts, artificial flavors/colors, stabilizers and/or preservatives. Examples include sodas, cereals, white bread, potato chips, and frozen ‘junk’ foods.
dementia danger and fast memory decline and Relevant low socioeconomic position and continuous low wage
Socioeconomic status (SES), which reflects both the social and economic assessment of an individual’s career and an individual’s or household’s economic access to resources and social status, is linked to both physical and mental health and well-being. Several studies have shown that socioeconomic poverty, including community vulnerability and persistent low wages, is associated with an increased risk of dementia, cognitive decline, and rapid memory decline.
- Individuals experiencing high socioeconomic poverty (measured using income/fortune, unemployment rates, car/home ownership, and housing density) are significantly more likely to develop dementia than individuals with higher genetic risk but higher socioeconomic status .
- Poor quality community resources and difficulty paying for basic needs were associated with lower scores on cognitive ability tests in black and Latino individuals.
- Persistent low-wage workers had a significantly faster rate of memory decline in old age compared to higher-paid workers.
- Higher parental socioeconomic status (SES) was associated with higher resilience to the negative effects of the Alzheimer’s disease marker ptau-181, better basic executive functioning, and a slower rate of cognitive decline in old age.
Alzheimer’s Association International conference® (AAIC)®) Introduce
The Alzheimer’s Association International Conference (AAIC) is the world’s largest gathering of researchers from around the world, focusing on Alzheimer’s and other dementia diseases. As part of the Alzheimer’s Association research program, the AAIC serves as a catalyst for building new knowledge regarding dementia and nurturing an important university-linked research community.
AAIC 2022 website: www.alz.org/aaic/ AAIC 2022 Newsroom: www.alz.org/aaic/pressroom.asp AAIC 2022 hashtag: #AAIC22
Alzheimer’s Association® Introduce
Alzheimer’s Association is a global voluntary health organization dedicated to Alzheimer’s treatment, support and research. The association’s mission is to lead the way to ending Alzheimer’s and all other dementia diseases by facilitating global research, reducing risk, maximizing early detection, quality treatment and support. The association’s vision is to support Alzheimer’s and all other dementias.® To create a disease-free world. alz.orgvisit or call 800.272.3900.
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