It took a woman 49 years to find out that she was a man. (Photo/Retrieved from Modern Express)
So bizarre! There is a 49-year-old woman in Huai’an, Jiangsu, China. She is 190 cm tall, dark-skinned, withdrawn and taciturn. Recently, she often felt weak in her lower limbs, so she went to the hospital for treatment. After the examination, she was surprised. In fact, it was a man, and this result made it difficult for her to accept.
According to the “Modern Express” report, the woman went to the doctor recently and found that her blood potassium was lower than 3.0mmol/l, which is hypokalemia. She went to the endocrinology department for further examination and found that the woman suffered from congenital adrenal hyperplasia. The upper body is too tall and the skin is dark. The doctor performed a chromosome and genetic examination on her, and the results were shocking, because the woman’s chromosomal karyotype was XY type, and the genetic test result was 17-hydroxylase deficiency, which is an extremely rare congenital Sex gene mutation disease.
In fact, the woman has never had menstruation since puberty, and she continued to grow taller. When she was 30 years old, she had the current height of 190 cm. She realized that she was different from others, so she felt extremely inferior and did not want to. Contact with people, but also to dispel the idea of marriage, has been living alone until now.
Physicians revealed that in the critical stage of fetal external genital development, androgen deficiency can lead to feminization of male fetuses, and 17-hydroxylase deficiency is a type of cause of abnormal sexual development, which can lead to cortisol and sex hormone synthesis pathways. Obstructed, the production is reduced, and the synthesis of mineralocorticoids is increased. Due to the lack of understanding of these diseases by family members and primary hospitals, and the atypical symptoms of patients, they are often misdiagnosed.
After the doctor gave the woman glucocorticoids and estrogen supplementation, her blood pressure decreased significantly. After improving hypokalemia and gradually reducing the antihypertensive drugs, she expected the patient to return to a normal life and establish confidence in actively coping with the disease.
