– The first transplant patient with a pig’s heart has died
The American, who died on Wednesday at the age of 57, had not made an immediate rejection of the organ. The researchers therefore consider the experiment a success.
The world’s first patient to receive a heart transplant from a genetically modified pig has died two months following his operation, the hospital where he was treated announced on Wednesday.
The operation, carried out on January 7, had raised great hopes, because such xenografts – from an animal to a human – might potentially make it possible to remedy the shortage of organ donations.
“Future Clinical Trials”
“The heart functioned very well for several weeks with no signs of rejection,” the hospital said. After the operation, “the patient was able to spend time with his family and participate in physiotherapy activities to help him regain his strength”.
The researchers therefore consider the experiment a success.
“We have obtained valuable information, and learned that a genetically modified pig’s heart can function properly inside a human body,” said Muhammad Mohiuddin, scientific director of the hospital’s xenotransplantation program. “We remain optimistic and plan to continue our work in future clinical trials.”
Genetically modified
The pig from which the transplanted heart came had been genetically modified in order to avoid an immediate rejection, which indeed did not take place.
Without this transplant, David Bennett was doomed. “It was either death or this transplant. I want to live,” he said the day before the operation.
“Until the end, my father wanted to keep fighting to save his life and spend more time with his family,” his son, David Bennett Jr., said in a statement.
“We were able to spend precious weeks together while he was recovering from his surgery, weeks that we would not have had without this miraculous effort”.
AFP
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