Recently, studies have shown that adult atopic dermatitis patients are at higher risk of osteoporosis and fractures. However, studies of Koreans have shown that current or past prevalence of atopic dermatitis does not clinically meanfully decrease bone density. However, the longer the prevalence of atopic dermatitis, or the lower the BMI, women are late to menarche, or the more the number of pregnancies, it has been shown to be associated with low bone density in the atopic patient group.
The team of Soo-young Kim, professor of Dermatology at Suncheon Hyang University Seoul Hospital and Kyung-jin Kim, professor of Endocrinology at Korea University Eye Cancer Hospital, used data from the National Health and Nutrition Survey from 2007 to 2009 to compare the bone density of atopic patients and healthy controls, and confirmed the relevant paper in an international journal entitled ‘Bone mineral density and osteoporosis risk in young adults with atopic dermatitis'(It was published in the latest issue of Scientific Report(SCI) on the 8th.
The researchers performed a 1:5 trend score weighted analysis for male and female adult atopic patients aged 19 years and under 50 years of age by matching the same age and sex, body mass index(BMI), vitamin D levels, and normal people in drinking and smoking conditions in multiples of 5. Analysis of 311 atopic patients and 8,972 control groups showed that lumbar bone density was significantly lower than that of the control group in the male atopic patients, but was not considered clinically meaningful within the error range reported in the existing literature. The prevalence of low bone density did not differ significantly from atopic patients and controls in both men and women.
However, the more atopic dermatitis is diagnosed at an early age, the longer the prevalence period, the lower the BMI, especially in women, the more late the menarche or the number of pregnancies, the more it was confirmed that there is an association with low bone density in the atopic patient group.
“However, female adult atopic patients who have had atopic dermatitis for a long period of time early, or have experienced pregnancy and childbirth need special attention to bone health,”Professor Soo-young Kim said.
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