Professor Dr. Her Royal Highness Princess Maha Chakri Sirindhorn Prince Chulabhorn Walailak empress Krom Phra Sri Sawangkhawat Worakatiya Rajanari The President of the Chulabhorn Research Institute came out at the Royal Throne Hall, Tamnak Thipiman, Pong Talong Subdistrict, Pak Chong District, Nakhon Ratchasima Province, giving a special lecture on the topic “Immune Therapy for Cancer Immuno-oncology”, bestowed upon the faculty members and students of the Faculty of Veterinary Medicine Faculty of Science and graduate school Kasetsart University For the academic year 2021, 50 students via electronic media (online). Today is the first day of the royal lecture on the topic. The Immune System and Cancer, which is cancer treatment by using a patient’s immune system to fight cancer cells in the body.
The immune system is heavily involved in the development of cancer. in normal people when there are cells in any part of the body begin to mutate to form cancer The immune system is responsible for eliminating the mutated cells. We survived cancer. but in people with weakened immune systems The mutated cells are not destroyed by the immune system. can become cancer immune system Therefore, it plays an important role in protecting health from the threat of germs. It can also help the performance of cells to function normally. and prevent cancer
In this, His Highness describes how the immune system works when foreign agents enter the body. The immune system is stimulated to get rid of the foreign body. that is, cancer cells leave the body. It is a new approach and an alternative to cancer treatment. with few side effects on patients It also gives patients a better quality of life than chemotherapy or radiation.
In addition, His Highness described the basic knowledge of the immune system, which can be divided into two types: Innate Immunity and Acquired or Adaptive Immunity, which work closely together. There is an immune surveillance system that can differentiate between normal cells (Self) and abnormal cells (Non-Self). Normally, cells in the immune system do not destroy body cells because of their ability to body cell recognition It can eliminate bacteria, viruses and foreign substances that are harmful to the body. Cells that are components of the innate immune system. will cause a general immune response Able to identify features at the molecular level on the cell surface of foreign or abnormal cells. without having to touch these things before and send a signal to call other cells of the immune system to that location To jointly attack and eliminate foreign cells quickly, such as eliminating germs that enter the body.
However, if the innate immune function is not effective enough A more specific immune system is needed. which will develop a memory of touching foreign cells before This creates a more effective response when exposed once more. On this occasion, His Highness gave examples of the mechanisms of action and responses of different types of cells in the immune system to gain a better understanding. He stressed the importance of the immune system in identifying cancer cells that originate from their own body’s own tissues as foreign. Although cancer cells used to be normal cells in the body. and get rid of foreign cells from the body without damaging the tissue itself, as well as giving examples of tumor antigens that stimulate the immune system response These antigens can be cancer markers used to diagnose the disease. and being used as a target for cancer treatment
Throughout this lecture His Highness brought the content obtained from His Majesty’s endeavor to study and research. and follow up on research progress Academics in the treatment of cancer in both humans and animals continuously. It is the greatest gratitude to the faculty members and students of Kasetsart University. gain a profound understanding of basic details This will lead to advances in cancer treatment for both humans and animals to be more effective in the future.
