(Taiwan English News/Comprehensive Report by the Pharmaceutical Group)Alzheimer’s diseaseIt is an irreversible degenerative disease. A study published in 2006 claimed that the main cause of the disease was related to the plaque accumulation of beta-amyloid in the brain. In the report titled “Stain”, neuroscientist Matthew Schrag of Vanderby University in the United States raised suspicions of fraud, which caused a great uproar in the academic world.
A 2006 paper by neuroscientist Sylvain Lesné of the University of Minnesota-Twin Cities in the academic journal “Nature” pointed out that the main cause of Alzheimer’s disease is related to the accumulation of beta-amyloid in the brain plaques , Therefore, in order to treat millions of Alzheimer’s patients around the world, in the past 16 years, scientists have tried various experiments and therapies to reduce the accumulation of beta-amyloid plaques in the brain, but have failed to prevent or prevent Exacerbation of Alzheimer’s disease.
By fate, Matthew Schrag, a neuroscientist at Vanderbilt University in the United States, came into contact with the experimental drug Simufilam developed by the American Cassava Sciences pharmaceutical company in 2021, and someone raised the suspicion that research related to the drug might be false. He took advantage of his own. Medical knowledge, following reviewing years of research and data, it was found that Sylvain Lesné was suspected of copying and pasting the research pictures in 2006. In early 2022, he submitted the relevant results to the National Institutes of Health (NIH) .
A half-year investigation by Science on the subject supported Matthew Schrag’s thesis while questioning Sylvain Lesné’s research. If it is really fake, it will undoubtedly be a big blow to the scientific community, and the hard work and money that have been invested over the years may be burned. As for Sylvain Lesné, he has not yet responded to the public.