2023-09-09 06:00:03
Researchers have just developed a brand new therapy capable of drastically slowing the growth of cancerous tumors. The method consists of making cancer cells absorb a very specific RNA fragment, which has the particularity of blocking cell division.
A new therapy once morest cancer uses microRNAs (micro RNAs (miRNA or mi RNA) are single-stranded RNAs approximately 21 to 24 long. .) to slow or stop the division of cancer cells.
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To date, cancers are treated by various methods, which nevertheless still have too little effectiveness or which are associated with significant side effects. The scientific community continues to carry out research to fight once morest this scourge. And the news in the field is rich! A few days ago in this article, we shared with you major news revealing a technique consisting of treating almost all cancers via the elimination of targeted chromosomes. Today it is the result of a completely different research (Scientific research refers primarily to all the actions undertaken with a view to…) but equally encouraging, that we are presenting to you.
The particularity of cancer cells lies in their ability to divide in a completely uncontrolled manner and evade the immune system. Researchers from the University of Purdue (United States), have just published the results of their work in the journal Oncogene, aiming to fight precisely once morest this specificity. As part of their research, they tested a brand new therapy on mice, consisting of administering a version of modified microRNA-34a. This molecule (A molecule is an electrically neutral chemical assembly of at least two atoms, which…), present in abundance in healthy cells and almost absent from cancer cells, has the particularity of slowing down or even stopping completely (The completely or completely automatic, or even by anglicism completion or…) cell division.
The results of the rodent tests were astonishing: tumors treated with this therapy did not increase in size in the 21-day monitoring period following administration of the molecule, whereas untreated tumors did. tripled in volume over the same period! Complete healing has thus been observed in certain animals. In addition to this demonstrated effectiveness, the molecule also made it possible to suppress for 120 hours (The hour is a unit of measurement:), the activity (The term activity can designate a profession.) of several genes which are known to cause cancer and also promote resistance to other anticancer therapies. These are the AXL, CD44 and MET genes.
The results of this research are the fruit of 15 years of work on the effectiveness of microRNAs once morest cancer. Researchers are confident regarding the long-term use of this method, which, combined with existing treatments, might succeed in defeating cancers that have developed resistance to drugs. The next step will consist of expanding the tests, and carrying out toxicity studies on a larger scale.
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