2023-09-16 06:00:06
According to a recent study, doing physical exercise reduces the risk of developing Alzheimer’s disease. The results of this study, recently published in the journal Neuron, explain how the secretion of a hormone during sport can have such an impactful effect in the slowdown (The slowdown signal (SNCF type) announces a needle (or several) in a deviated position…) of this disease (The disease is an alteration of the functions or health of a living organism, animal… ) so devastating.
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Researchers at Massachusetts General Hospital recently discovered that the hormone irisin, which is secreted in the body when we exercise, may have a direct link to the reduction of deposits of a protein in cells. brain: beta-amyloid. However, the deposition of this protein creates plaques in the brain (The brain is the main organ of the central nervous system of animals. The brain processes…) and it is precisely these plaques which are at the origin of the specific symptoms of Alzheimer’s disease.
To reach this conclusion, the researchers previously found that in the brains of humans and mice, the level of irisin in patients with Alzheimer’s disease was very reduced. They then attempted to apply irisin to an advanced 3D model of culture (UNESCO’s definition of culture is as follows: [1] 🙂 of human Alzheimer’s disease cells, and were thus able to observe that irisin generated significant activity of an enzyme (An enzyme is a molecule (protein or RNA in the case of ribozymes) allowing…) called “neprilysin”, and that this activity had the effect of degrading beta-amyloid, thus significantly reducing its deposition.
If a link was already presumed between physical exercise and the reduction of beta-amyloid deposits, the precise mechanisms were until now unknown. According to the results of 11 other studies carried out in the field, regular exercise could reduce the risk of developing dementia by around 30%. %, and this rate can reach 45% for Alzheimer’s disease alone. Other studies have also already demonstrated that when irisin is injected into the blood of mice, it can penetrate the brain, which makes it possible to consider therapeutic use (Therapeutics (from the Greek therapeuein, to treat) is the part of medicine which…).
The results of this study are encouraging, when we know that every year, 10 million new people around the world are diagnosed with dementia (The word world can refer to:). Figure (A number is a symbol used to represent numbers.) which continues to increase, and which could actually double every 20 years. The practice of physical activity (Physical activity includes both physical exercise in daily life, at home, etc.) definitely has many advantages: you can also find our recent publications on the effectiveness of a physical activity (Physics (from the Greek φυσις, nature) is etymologically the…) of a few minutes (Primary form of a document: Law: a minute is the original of an act. … ) only per day to reduce the risk of cancer (Cancer is a disease characterized by abnormal cell proliferation…) (link to the article), or on the number (The notion of number in linguistics is treated at article “Number…) of steps to take each day for this activity to have an effect on our lifespan (link to the article).
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